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Compression of Whole Genome Alignments | IEEE Journals & Magazine | IEEE Xplore

Compression of Whole Genome Alignments


Abstract:

Recent advances in DNA sequencing technology have caused an exponential growth of publicly available genomic sequence data. A particularly voluminous, frequently used sta...Show More

Abstract:

Recent advances in DNA sequencing technology have caused an exponential growth of publicly available genomic sequence data. A particularly voluminous, frequently used static data set are whole genome alignments. The first lossless compression algorithm for such data sets based on well-established statistical evolutionary models and prediction techniques from lossless binary image compression is introduced. The compression rate is improved by a factor of 1.6 compared to the currently used Lempel-Ziv (LZ) compression.
Published in: IEEE Transactions on Information Theory ( Volume: 56, Issue: 2, February 2010)
Page(s): 696 - 705
Date of Publication: 25 February 2010

ISSN Information:


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