Decentralized cryptocurrency systems have become primary targets for attackers due to substantial profit gain and economic rewards. A number of attack models have been proposed during last few years. However, the evaluation and comparison of those attack models remain problematic due to the lack of systematic framework to analyze them. In this work, we propose a general quantitative analysis framework for attack models in the network and consensus layer of blockchain. We identify the problem statement and evolution process. And we show how to apply our general framework in previous attacks such as selfish mining and bribery attack. We also explained that the framework is suitable for other attacks in blockchain. For further exploration, we simulate the success rate and benefits of different attacks through experiments. We provide several defensive strategies, and study how these strategies against previous attack models.