In large-scale satellite networks, data delivery confronts obvious challenges such as high loss rate and long propagation delay leading to low Packet Delivery Ratio (PDR) and huge delivery latency over intermittent Inter-Satellite Links (ISLs), making the current routing algorithms exploiting typical Automatic Repeat reQuest (ARQ) mechanisms extremely inefficient and even incapable. To address this issue, in this paper, we propose a semantic-aware coding and routing joint mechanism called Semantic Adaptive Coding and Routing (SACR) by considering both the semantic correlations in the context-dependent data and the link status knowledge. In particular, the proposed SACR achieves excellent error-tolerant and routing-agile capabilities by an elaborately interactive design consisting of a customized routing-aware Semantic Adaptive Coding Hybrid ARQ (SAC-HARQ) mechanism and a Semantic Coding-based Routing Mechanism (SCRM). The simulation results indicate that the proposed SACR mechanism performs better in reducing the average delivery latency and improving the effective throughput compared with typical routing mechanisms such as Open Shortest Path First (OSPF) routing, Deep Q-Networks based Intelligent Routing (DQN-IR), and Real-Time Hop-by-hop routing (RTHop), integrating with typical semantic coding methods, i.e., Deep Learning-based Joint Channel-Source Coding (DL-JSCC), Deep learning-based Semantic Communication system (DeepSC), and Semantic Coding HARQ (SCHARQ), respectively.