This paper is concerned with the consensus problem of general linear dynamic multiagent systems with stochastic sampling. In this paper, the sampling intervals randomly switch between two different values. The communication topology between agents is fixed and directed. Full- and reduced-order observers are designed based on neighbor agents' relative output information. The algorithms to construct such observers are also provided. By using the estimated states of the agents, the observer-based consensus protocol with stochastic sampling are presented. Sufficient conditions to ensure consensus in mean square are derived by using Lyapunov stability theory. Finally, simulations are given to examine the effectiveness of the proposed methods.