The DC-DC converter for fuel cell vehicles should be characterized by high-gain, low voltage stress, small size and high-efficiency. However, conventional two-level, three-level and cascaded boost converters cannot meet the requirements. A new non-isolated DC-DC converter with switched-capacitor and switched-inductor is proposed in this paper, which can obtain high-gain, wide input voltage range, low voltage stresses across components and common ground structure. In this paper, the operating principle, component parameters design, and comparisons with other high-gain converters are analyzed. Moreover, the state-space averaging method and small-signal modeling method are adopted to obtain the dynamic model of converter. Finally, simulation and experimental results verify the effectiveness of the proposed topology. The input voltage of the experimental prototype ranges from 25 V to 80 V. The rated output voltage is 200 V and rated power is 100W. The maximum efficiency is 93.1% under rated state. The proposed converter is suitable for fuel cell vehicles.