EVE (Exercise in Virtual Environments) is an operational VR system designed for space, polar and submarine crews. This system allows crewmembers — living and working in artificial habitats- to explore immersive natural landscapes during their daily physical exercise, and experience presence in a variety of alternate environments. Using recent hardware and software, this innovative psychological counter-measure aims at reducing the adverse effects of confinement and monotony in long duration missions, while maintaining motivation for physical exercise. Initial testing with a proof-of-concept prototype was conducted near the South magnetic pole, as well as in transient microgravity.