The Long Term Evolution (LTE) standard is one of the most promising technologies of wireless network for the development of Machine-to-Machine (M2M) communication because of its high data rates, low latency, high flexibility and low cost. However, improvements are needed in the network to support the uplink-heavy traffic generated by M2M communication and also to ensure the diversity of service requirements of this communication. The uplink packet scheduler is included in the necessary improvements. In this article, we evaluate the performance of the main schedulers for M2M communication regarding the aspects of service requirements, fairness, energy efficiency and impact on the system performance of current LTE traffic.