Automated detection of microcalcification clusters in mammograms

Vikrant A. Karale; Sudipta Mukhopadhyay; Tulika Singh; Niranjan Khandelwal; Anup Sadhu

doi:10.1117/12.2254330

3 March 2017 Automated detection of microcalcification clusters in mammograms

Vikrant A. Karale, Sudipta Mukhopadhyay, Tulika Singh, Niranjan Khandelwal, Anup Sadhu

Proceedings Volume 10134, Medical Imaging 2017: Computer-Aided Diagnosis; 101342R (2017) https://doi.org/10.1117/12.2254330
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

Mammography is the most efficient modality for detection of breast cancer at early stage. Microcalcifications are tiny bright spots in mammograms and can often get missed by the radiologist during diagnosis. The presence of microcalcification clusters in mammograms can act as an early sign of breast cancer. This paper presents a completely automated computer-aided detection (CAD) system for detection of microcalcification clusters in mammograms. Unsharp masking is used as a preprocessing step which enhances the contrast between microcalcifications and the background. The preprocessed image is thresholded and various shape and intensity based features are extracted. Support vector machine (SVM) classifier is used to reduce the false positives while preserving the true microcalcification clusters. The proposed technique is applied on two different databases i.e DDSM and private database. The proposed technique shows good sensitivity with moderate false positives (FPs) per image on both databases.

Citation Download Citation

Vikrant A. Karale, Sudipta Mukhopadhyay, Tulika Singh, Niranjan Khandelwal, and Anup Sadhu "Automated detection of microcalcification clusters in mammograms", Proc. SPIE 10134, Medical Imaging 2017: Computer-Aided Diagnosis, 101342R (3 March 2017); https://doi.org/10.1117/12.2254330

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