Paper
23 February 2010 A system for advanced real-time visualization and monitoring of MR-guided thermal ablations
Eva Rothgang, Wesley D. Gilson, Joachim Hornegger, Christine H. Lorenz
Author Affiliations +
Abstract
In modern oncology, thermal ablations are increasingly used as a regional treatment option to supplement systemic treatment strategies such as chemotherapy and immunotherapy. The goal of all thermal ablation procedures is to cause cell death of disease tissue while sparing adjacent healthy tissue. Real-time assessment of thermal damage is the key to therapeutic efficiency and safety of such procedures. Magnetic resonance thermometry is capable of monitoring the spatial distribution and temporal evolution of temperature changes during thermal ablations. In this work, we present an advanced monitoring system for MR-guided thermal ablations that includes multiplanar visualization, specialized overlay visualization methods, and additional methods for correcting errors resulting from magnetic field shifts and motion. To ensure the reliability of the displayed thermal data, systematic quality control of thermal maps is carried out on-line. The primary purpose of this work is to provide clinicians with an intuitive tool for accurately visualizing the progress of thermal treatment at the time of the procedure. Importantly, the system is designed to be independent of the heating source. The presented system is expected to be of great value not only to guide thermal procedures but also to further explore the relationship between temperature-time exposure and tissue damage. The software application was implemented within the eXtensible Imaging Platform (XIP) and has been validated with clinical data.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Eva Rothgang, Wesley D. Gilson, Joachim Hornegger, and Christine H. Lorenz "A system for advanced real-time visualization and monitoring of MR-guided thermal ablations", Proc. SPIE 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, 762522 (23 February 2010); https://doi.org/10.1117/12.844203
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KEYWORDS
Visualization

Tissues

Magnetic resonance imaging

Temperature metrology

Thermometry

Liver

Scanners

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