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Determining miRNA-disease associations using bipartite graph modelling

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Published:22 September 2013Publication History

ABSTRACT

Exploring miRNA-disease interactions is critical to identify the impact of a disease on other diseases. Mapping this problem to a graph theoretical concept offers a unique perspective to study unseen relationships among diseases. In our work, maximum weighted matching has been used after mapping the miRNA-disease associations as a bipartite graph. We also address the limitation of this approach using disease ranking scheme and the results are presented.

References

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  4. Q. Yang, C. Qiu, J. Yang, Q. Wu, and Q. Cui. mirenvironment database: providing a bridge for micrornas, environmental factors and phenotypes. Bioinformatics, 27(23):3329--3330, 2011. Google ScholarGoogle ScholarDigital LibraryDigital Library

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              • Published in

                cover image ACM Conferences
                BCB'13: Proceedings of the International Conference on Bioinformatics, Computational Biology and Biomedical Informatics
                September 2013
                987 pages
                ISBN:9781450324342
                DOI:10.1145/2506583

                Copyright © 2013 Owner/Author

                Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the Owner/Author.

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                Association for Computing Machinery

                New York, NY, United States

                Publication History

                • Published: 22 September 2013

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                • tutorial
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                • Refereed limited

                Acceptance Rates

                BCB'13 Paper Acceptance Rate43of148submissions,29%Overall Acceptance Rate254of885submissions,29%

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