This paper investigates the uplink throughput performance and the interference power to other cells using an Evolved UTRA (E-UTRA) laboratory and field experimental system. In E-UTRA uplink, the near-far problem is not an issue since the orthgonality among the users within the target cell is maintained. Therefore, the fractional transmission power control (TPC), in which the target level of TPC is adjusted according to the path loss level, can be adopted. Thus, it is expected the high cell throughput and the large coverage area by combining fractional TPC, adaptive modulation and channel coding (AMC), and variable resource block (RB) allocation. The indoor and field experimental results show that the peak throughput of approximately 45Mbps is achieved by allocating a wider bandwidth and setting higher target level for the UE located near the cell site while keeping the adjacent cell interference level almost the constant. We also showed that the system capacity can be improved by 50% in simple cell model by applying the AMC and the fractional TPC.