MIMO-OFDM combining OFDM and MIMO techniques achieves high spectral efficiency and is able to increase throughput. MIMO-OFDM systems can be classified into either “open loop” or “closed loop” depending on whether the CSI is fed back from the Rx to the Tx. As a closed loop scheme, SVD-MIMO is the optimal single user MIMO-OFDM transmission scheme while it requires knowledge of the CSI at both the Tx and Rx. In practical systems, Tx weight is fed back from the Rx to the Tx by limited bits and with feedback delay, which causes mismatch between the weight and the real channel especially if the channel exhibits time variation. Hence, the transmission performance of the SVD-MIMO scheme degrades. Therefore, the performance comparison between open loop and closed loop schemes against channel variation is very important for practical deployment of MIMO-OFDM systems. For that purpose, a unified performance calculation method for the open loop and the closed loop MIMO-OFDM schemes with finite and delayed feedback is developed in this paper. The method is effective for analysis of both STBC for the open loop and SVD-MIMO using codebook for the closed loop with per stream layer AMC. Also, to combat frequency selective fading in practical wireless channels, an interleaver is employed in this paper. In numerical analyses, it is found that simulation results agree well with the derived theoretical performance results. Secondly, from these results, the cross-over point of the throughput performance of two schemes in terms of UE velocity and SNR is found.