Coaxial connectors are extensively used in electrical systems and the degradation of the connector can alter the signal that is being transmitted and leads to faults, which is one of the major causes of low communication quality. In this work, the failure features caused by the degraded connector contact surface were studied. The relationship between the DC resistance and decreased real contact areas was given. Considering the inductance properties and capacitive coupling at high frequencies, the impedance characteristics of the degraded connector were discussed. Based on the transmission line theory and experimental measurement, an equivalent lump circuit of the coaxial connector was developed. For the degraded contact surface, the capacitance was analyzed, and the frequency effect was investigated. According to the high frequency characteristics of the degraded connector, a fault detection and location method for coaxial connectors in RF system was developed using a neural network method. For connectors suffering from different levels of pollution, their impedance modulus varies continuously. Considering the range of the connector's impedance parameters, the fault modes were determined. Based on the scattering parameter simulation of a RF receiver front-end circuit, the S₁₁ and S₂₁ parameters were obtained as feature parameters and Monte Carlo simulations were conducted to generate training and testing samples. Based on the BP neural network algorithm, the fault modes were classified and the results show the diagnosis accuracy was 97.33%.