In this letter, we analyze the average symbol error rate (SER) performance for multiple-input multiple-output (MIMO) wireless communication links with transmit beamforming and maximum ratio combining (MRC), known as MIMO-MRC, in the presence of multiple interferers in Rayleigh fading channels. An upper bound and an approximation of the average SER for M-ary signaling and an exact average SER for some modulation formats are evaluated. Moreover, an exact closed-form expression of the average SER in an interference-limited environment is derived. The analytical results are confirmed by numerical simulations.