In this paper, we investigate two receiver structures for spatially multiplexed transmission on MIMO frequency selective fading channels. Those receivers compensate the IAI (Inter-Antenna Interference) and ISI (Inter-Symbol Interference) in the time domain. We first propose the MIMO sequential equalizer in which the block of several receives symbols is processed symbol by symbol by MLD (Maximum Likelihood Detection). Next we investigate the MIMO MLSE (Maximum Likelihood Sequence Estimation) receiver in which the terminated block trellis is decoded by the Viterbi algorithm. The bit error rates of two time domain receivers are examined through computer simulations and we also compare their BER characteristics to those of the conventional MIMO SC-FDE.