Recently, Li and Xia proposed a physical-layer security design to guarantee a low probability of interception (LPI) for asynchronous cooperative systems without relying on upper-layer data encryption. The proposed scheme utilizes diagonal unitary codes to perform different encoding in the frequency domain over subcarriers within each OFDM block to randomize the transmitted signals. To build on their idea, in this letter, a subcarrier-reference (SR) transmission scheme is proposed with deliberate signal randomization to achieve LPI in multiuser MISO-OFDMA systems. For each user, one of the allocated subcarriers is chosen by the transmitter to send reference signals, and others are chosen to send the user's information symbols. By some deliberate signal randomization, the eavesdropper cannot detect the transmitted symbols, while the authorized users can operate the system successfully without knowledge of the channels by subcarrier-reference demodulation. Extensive simulations are conducted to demonstrate the scheme's effectiveness.