In this paper, we propose a power amplifier linearization technique combined with iterative noise cancelation. This method alleviates the effect of added noises which prevents the predistorter (PD) from estimating the exact characteristics of the power amplifier (PA). To iteratively cancel the noise added in the feedback signal, the output signal of the power amplifier without noise is reconstructed by applying the inverse characteristics of the PD to the predistorted signals. The noise can be revealed by subtracting the reconstructed signals from the feedback signals. Simulation results based on the mean-square error (MSE) and power spectral density (PSD) criteria are presented to evaluate PD performance. The results show that the iterative noise cancelation significantly enhances the MSE performance, which leads to an improvement of the out-of-band power suppression. The performance of the proposed technique is verified by computer simulation and hardware test results.