In this correspondence, two types of multiple binary zero correlation zone (ZCZ) sequence sets with inter-set zero cross-correlation zone (ZCCZ) are constructed. Based on orthogonal matrices with order N×N, multiple binary ZCZ sequence sets with inter-set even and odd ZCCZ lengthes are constructed, each set is an optimal ZCZ sequence set with parameters (2N², N, N+1)-ZCZ, among these ZCZ sequence sets, sequences possess ideal cross-correlation property within a zone of length 2Z or 2Z+1. These resultant multiple ZCZ sequence sets can be used in quasi-synchronous CDMA systems to remove the inter-cell interference (ICI).