For the acquisition of visual information, the nonuniform sampling process by photoreceptors on the retina occurs at the earliest stage of visual processing. From objects of interest, the human eye receives high visual resolution through nonuniform distribution of photoreceptors. Therefore, this paper proposes auto exposure and focus algorithms for the real-time video camera system based on the visual characteristic of the human eye. For given moving objects, the visual weight is modeled for quantifying the visual importance and the associated auto exposure and focus parameters are derived by applying the weight to the traditional numerical expression, i.e., the DoM (Difference of Median) and Tenengrad methods for auto focus.