Deep Neural Networks (DNNs) have been widely used in object detection, image classification, natural language processing, speech recognition, and other fields. Nevertheless, DNNs are vulnerable to adversarial examples which are formed by adding imperceptible perturbations to original samples. Moreover, the same perturbation can deceive multiple classifiers across models and even across tasks. The cross-model transfer characteristics of adversarial examples limit the application of DNNs in real life, and the threat of adversarial examples to DNNs has stimulated researchers' interest in adversarial attacks. Recently, researchers have proposed several adversarial attack methods, but most of these methods (especially the black-box attack) have poor cross-model attack ability for defense models with adversarial training or input transformation in particular. Therefore, this study proposes a method to improve the transferability of adversarial examples, namely, RLI-CI-FGSM. RLI-CI-FGSM is a transfer-based attack method, which employs the gradient-based white-box attack RLI-FGSM to generate adversarial examples on the substitution model and adopts CIM to expand the source model so that RLI-FGSM can attack both the substitution model and the extended model at the same time. Specifically, RLI-FGSM integrates the RAdam optimization algorithm into the Iterative Fast Gradient Sign Method (I-FGSM) and makes use of the second-derivative information of the objective function to generate adversarial examples, which prevents the optimization algorithm from falling into a poor local optimum. Based on the color invariance property of DNNs, CIM optimizes the perturbations of image sets with color transformation to generate adversarial examples that can be transferred and are less sensitive to the attacked white-box model. Experimental results show that the proposed method has a high success rate on both normal and adversarial network models.