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In this paper, we analyse the services supplied by innovative and transversal healthcare organisations to satisfy patients and large public requirements and we illustrate them with the French healthcare networks. We classes these services in two groups, healthcare delivery services and health related information services, and we define three layers for their possible contexts. We will use an Information System perspective to investigate about various methodological approaches to realise each group of services and we compare their challenges and difficulties. Finally, we identify methodological and engineering issues common to both groups.
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