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Current Omics Technologies in Biomarker Discovery

Current Omics Technologies in Biomarker Discovery

Wei Ding, Ping Qiu, Yan-Hui Liu, Wenqing Feng
Copyright: © 2011 |Pages: 33
ISBN13: 9781609604912|ISBN10: 1609604911|EISBN13: 9781609604929
DOI: 10.4018/978-1-60960-491-2.ch004
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MLA

Ding, Wei, et al. "Current Omics Technologies in Biomarker Discovery." Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications, edited by Limin Angela Liu, et al., IGI Global, 2011, pp. 79-111. https://doi.org/10.4018/978-1-60960-491-2.ch004

APA

Ding, W., Qiu, P., Liu, Y., & Feng, W. (2011). Current Omics Technologies in Biomarker Discovery. In L. Liu, D. Wei, Y. Li, & H. Lei (Eds.), Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications (pp. 79-111). IGI Global. https://doi.org/10.4018/978-1-60960-491-2.ch004

Chicago

Ding, Wei, et al. "Current Omics Technologies in Biomarker Discovery." In Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications, edited by Limin Angela Liu, et al., 79-111. Hershey, PA: IGI Global, 2011. https://doi.org/10.4018/978-1-60960-491-2.ch004

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Abstract

Biomarkers are playing an increasingly important role in drug discovery and development and can be applied for many purposes, including disease mechanism study, diagnosis, prognosis, staging, and treatment selection. Advances in high-throughput “omics” technologies, including genomics, transcriptomics, proteomics and metabolomics, significantly accelerate the pace of biomarker discovery. Comprehensive molecular profiling using these “omics” technology has become a field of intensive research aiming at identifying biomarkers relevant for improved diagnostics and therapeutics. Although each “omics” technology plays important roles in biomarker research, different “omics” platforms have different strengths and limitations. This chapter aims to give an overview of these “omics” technologies and their current application in the biomarker discovery.

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