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Cancer and Signaling Pathway Deregulation

Cancer and Signaling Pathway Deregulation

Yingchun Liu
Copyright: © 2011 |Pages: 11
ISBN13: 9781609604912|ISBN10: 1609604911|EISBN13: 9781609604929
DOI: 10.4018/978-1-60960-491-2.ch017
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MLA

Liu, Yingchun. "Cancer and Signaling Pathway Deregulation." Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications, edited by Limin Angela Liu, et al., IGI Global, 2011, pp. 369-379. https://doi.org/10.4018/978-1-60960-491-2.ch017

APA

Liu, Y. (2011). Cancer and Signaling Pathway Deregulation. In L. Liu, D. Wei, Y. Li, & H. Lei (Eds.), Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications (pp. 369-379). IGI Global. https://doi.org/10.4018/978-1-60960-491-2.ch017

Chicago

Liu, Yingchun. "Cancer and Signaling Pathway Deregulation." In Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications, edited by Limin Angela Liu, et al., 369-379. Hershey, PA: IGI Global, 2011. https://doi.org/10.4018/978-1-60960-491-2.ch017

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Abstract

Cancer is a complex disease that is associated with a variety of genetic aberrations. The diagnosis and treatment of cancer have been difficult because of poor understanding of cancer and lack of effective cancer therapies. Many studies have investigated cancer from different perspectives. It remains unclear what molecular mechanisms have triggered and sustained the transition of normal cells to malignant tumor cells in cancer patients. This chapter gives an introduction to the genetic aberrations associated with cancer and a brief view of the topics key to decode cancer, from identifying clinically relevant cancer subtypes to uncovering the pathways deregulated in particular subtypes of cancer.

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