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Ghostly intrusion on a frightful Halloween night: a case report of dual valve endocarditis

Authors

Multivalvular endocarditis (MVE) is an uncommon presentation and mostly involves mitral and aortic valves. Here, we present a case of an MVE with an unusual and bizarre presentation on a Halloween night with a massive degree of valve destruction and right- and left-side involvement requiring emergent surgery. A 51-year-old male patient with intravenous drug usage presented with anorexia, fever, and dyspnea, rapidly progressing to septic shock with multiorgan dysfunction. Initial blood cultures detected meticillin-sensitive Staphylococcus aureus, and antibiotic therapy was started. Transesophageal echocardiography revealed extensive valve destruction of both mitral and tricuspid valves, namely a mitral valve with large vegetation resembling a ghostly figure, causing severe mitral regurgitation. The patient was transferred for emergent mitral and tricuspid surgery. The particularity of this case, besides the bizarre images, is that, as a drug user, there are specific considerations regarding surgical strategy and options in this scenario that we discussed here.

Delgado V, Marsan NA, de Waha S, et al. 2023 ESC guidelines for the management of endocarditis. Developed by the task force on the management of endocarditis of the European Society of Cardiology. Eur Heart J 2023;44:3948-4042. DOI: https://doi.org/10.1093/eurheartj/ehad625
Lazar HL. Valve surgery for endocarditis in patients who inject drugs: removing them from the society of thoracic surgeons database is only part of the solution. J Am Heart Assoc 2021;10:e021153. DOI: https://doi.org/10.1161/JAHA.121.021153
Zubarevich A, Szczechowicz M, Osswald A, et al. Surgical treatment of infective endocarditis in intravenous drug abusers. J Cardiothorac Surg 2021;16:97. DOI: https://doi.org/10.1186/s13019-021-01491-1
Østerdal OB, Salminen P-R, Jordal S, et al. Cardiac surgery for infective endocarditis in patients with intravenous drug use. Interact CardioVasc Thorac Surg 2016;22:633-40. DOI: https://doi.org/10.1093/icvts/ivv397
Baddour LM, Weimer MB, Wurcel AG, et al. Management of infective endocarditis in people who inject drugs: a scientific statement from the American Heart Association. Circulation 2022;146:e187-201. DOI: https://doi.org/10.1161/CIR.0000000000001090

How to Cite

Castro, Margarida, Mariana Tinoco, Rafael Martins, Mário Jorge Amorim, Luísa Pinheiro, Marina Fernandes, Filipa Cardoso, et al. 2025. “Ghostly Intrusion on a Frightful Halloween Night: A Case Report of Dual Valve Endocarditis”. Monaldi Archives for Chest Disease, January. https://doi.org/10.4081/monaldi.2025.3228.

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