8th International Conference on Bio-inspired Information and Communications Technologies (formerly BIONETICS)

Research Article

Modeling Self-organization of Microtubules from Tubulins

  • @INPROCEEDINGS{10.4108/icst.bict.2014.257891,
        author={Somenath Das and Ramana Pidaparti and Preetam Ghosh},
        title={Modeling Self-organization of Microtubules from Tubulins},
        proceedings={8th International Conference on Bio-inspired Information and Communications Technologies (formerly BIONETICS)},
        publisher={ICST},
        proceedings_a={BICT},
        year={2015},
        month={2},
        keywords={self-organization microtubules},
        doi={10.4108/icst.bict.2014.257891}
    }
    
  • Somenath Das
    Ramana Pidaparti
    Preetam Ghosh
    Year: 2015
    Modeling Self-organization of Microtubules from Tubulins
    BICT
    ACM
    DOI: 10.4108/icst.bict.2014.257891
Somenath Das1, Ramana Pidaparti1,*, Preetam Ghosh2
  • 1: University of Georgia
  • 2: Virginia Commonwealth University
*Contact email: rmparti@uga.edu

Abstract

Self-assembly is a ubiquitous, naturally occurring, robust process in many living organisms. Microtubules are a well-studied type of natural self-organization systems that assemble into functional units by attaching to cellular structures. Modeling microtubule self-organization is of broad interest as they form a network of protein filaments that is critical to many processes in eukaryotic cells. In this paper, we propose a modeling algorithm starting from alpha and beta tubulins as basic building blocks in the self-organization of microtubules. The preliminary results obtained from our algorithm demonstrate that such self-organization stems from the properties of the basic building blocks that can be used to form the complex microtubule structures.