Abstract
A method to measure spatial and temporal brain deformation from sequential intraoperative Magnetic Resonance Images (MRI) and its preliminary clinical results are reported. Deformation is estimated with a volumetric optical flow measurement based on local intensity differences. A multi-resolution approach was used to efficiently estimate the deformation. We applied the method to five different cases and the method is highlighted by illustrative features accompanied by five sets of intraoperative MRI scanned before and after dura opening, twice during tumor resection and immediately after dura closure. The maximum cortical surface shift measured was 11 mm and subsurface shift was 4 mm. Volume change was measured by aligning the sequence of intraoperative MR images immediately after the opening of the dura to the images during the tumor resection. The amount of deformation present at each stage of the surgery was visualized. The computed deformation field was most satisfactory when the skin was first segmented and removed from the images prior to the optical flow computation. Magnetic field inhomegeneities as well as administration of contrast agent (Gadolinium-DTPA) were observed to modify the deformation field. The method demonstrated a good capability of intra-operative surface, subsurface and midline shift measurement.
Chapter PDF
Similar content being viewed by others
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
Koivukangas, J., Louhisalmi, Y., Alakuijala, J., Oikarinen, J.: Ultrasoundcontrolled neuronavigator-guided brain surgery. J. Neurosurg. 79, 36–42 (1993)
Kato, A., Yoshimine, T., Hayakawa, T., Tomita, Y., Ikeda, T., Mitomo, M., Harada, K., Mogami, H.: A frameless, armless navigation system for computer-assisted neurosurgery. J. Neurosurg. 74, 845–849 (1991)
Barron, J.L., Fleet, D.J., Beauchemin, S.S.: Performance of optical flow techniques. Intnational J. Comp. Vision 12, 43–77 (1994)
Horn, B.K.P., Schunck, B.G.: Determining optical flow. AI 17, 185–204 (1986)
Ewing, G.M.: Calculus of Variations with Applications. Dover Publications, Mineola (1985)
Hamming, R.: Numerical Methods for Scientists and Engineers, 2nd edn. Dover Pubns, Mineola (1987)
Viola, P.A.: Alignment by Maximization of Mutual Information. In: Artificial Intelligence Laboratory, p. 155. Massachusetts Institute of Technology, Cambridge (1995)
Wells III, W.M., Viola, P., Atsumi, H., Nakajima, S., Kikinis, R.: Multi-Modal Volume Registration by Maximization of Mutual Information. Medical Image Analysis 1, 35–51 (1996)
Trobaugh, J.W., Richard, W.D., Smith, K.R., Bucholz, R.D.: Frameless stereotactic ultrasonography: method and applications. Comput. Med. Imaging Graph 18, 235–246 (1994)
Bucholtz, R., Trobaugh, D.Y.J., McDurmont, L., Sturm, C., Baumann, C., Henderson, J., Levy, A., Kessman, P.: The correction of stereotactic inaccuracy by brain shift using an intraoperative ultrasound device. In: Troccaz, J., Mösges, R., Grimson, W.E.L. (eds.) CVRMed-MRCAS 1997, CVRMed 1997, and MRCAS 1997. LNCS, vol. 1205. Springer, Heidelberg (1997)
Hill, D.L., Maurer Jr., C.R., Maciunas, R.J., Barwise, J.A., Fitzpatrick, J.M., Wang, M.Y.: Measurement of intraoperative brain surface deformation under a craniotomy. Neurosurgery 43, 514-526; discussion 527–528 (1998)
Roberts, D.W., Hartov, A., Kennedy, F.E., Miga, M.I., Paulsen, K.D.: Intraoperative brain shift and deformation: a quantative analysis of cortical displacement in 28 cases. Neurosurgery 43, 749–760 (1998)
Freeborough, P.A., Fox, N.C.: Modeling brain deformations in Alzheimer disease by fluid registration of serial 3D MR images. J. Comput. Assist. Tomogr. 22, 838–843 (1998)
Chiristensen, G.E., Rabbitt, R.D., Miller, M.I.: Deformable templates using large deformation kinematics. IEEE Trans. Image Proc. 5, 1435–1447 (1996)
Maurer, C.R., Hill, D.L.G., Martin, A.J., Liu, H., McCue, M., Rueckert, D., Lloret, D., Hall, W.A., Maxwell, R.E., Hawkes, D.J., Truwit, C.L.: Investigation of intraoperative brain deformation using a 1.5T interventional MR system: preliminary results. IEEE Trans. Med. Img. 17, 817–825 (1998)
Studholme, C., Hill, D.L.G., Hawkes, D.J.: Automated 3D registration of truncated MR and CT images of the head. Presented at British medicine vision conference (1995)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Hata, N., Nabavi, A., Warfield, S., Wells, W., Kikinis, R., Jolesz, F.A. (1999). A Volumetric Optical Flow Method for Measurement of Brain Deformation from Intraoperative Magnetic Resonance Images. In: Taylor, C., Colchester, A. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI’99. MICCAI 1999. Lecture Notes in Computer Science, vol 1679. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10704282_101
Download citation
DOI: https://doi.org/10.1007/10704282_101
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-66503-8
Online ISBN: 978-3-540-48232-1
eBook Packages: Springer Book Archive