Abstract
A multiple modeling algorithm for antibiotic fermentation process based on fuzzy c-means (FCM) and support vector regression (SVR) is proposed. By analyzing the features of antibiotic fermentation, the mechanism of multiple modeling of the bioprocess is presented. Using FCM clustering method, the bioprocess is classified into several work states and sub-models. Then, taking advantage of the generalization properties of SVR, the multiple model of bioprocess is established and the proposed algorithm is described. Experimental data of industrial penicillin production is used to validate the model.
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References
Xiong, Z., Zhang, J.: Modeling and Optimal Control of Fed-Batch Processes Using Control Affme Feedforward Neural Networks. In: Proceedings of the American Control Conference, vol. 6, pp. 5025–5030 (2002)
Hodge, D., Simon, L., Karim, M.N.: Data Driven Approaches to Modeling and Analysis of Bioprocesses: Some Industrial Examples. In: Proceedings of the American Control Conference, vol. 3, pp. 2062–2076 (2003)
Bezdek, J.C.: Pattern Recognition with Fuzzy objective function algorithm. Plenum Press, New York (1981)
Cannon, R.L., Dave, J., Bezdek, J.C.: Efficient implementation of the fuzzy c means clustering algorithms. IEEE Trans. Pattern Anal. Machine Intell. 8, 248–255 (1986)
Vapnik, V.: Statistical Learning Theory. Wiley, New York (1998)
Vapnik, V.: The nature of statistical learning theory. Springer, New York (1995)
Burges, C.J.C.: A tutorial on support vector machines for pattern recognition. Data Mining and Knowledge Discovery 2 2, 121–167 (1998)
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© 2005 Springer-Verlag Berlin Heidelberg
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Xue, Y., Yuan, J. (2005). A SVR-Based Multiple Modeling Algorithm for Antibiotic Fermentation Process Using FCM. In: Wang, J., Liao, XF., Yi, Z. (eds) Advances in Neural Networks – ISNN 2005. ISNN 2005. Lecture Notes in Computer Science, vol 3498. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11427469_110
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DOI: https://doi.org/10.1007/11427469_110
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-25914-5
Online ISBN: 978-3-540-32069-2
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