Skip to main content

DNA-Based Computation Times

  • Conference paper
DNA Computing (DNA 2004)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3384))

Included in the following conference series:

Abstract

Speed of computation and power consumption are the two main parameters of conventional computing devices implemented in microelectronic circuits. As performance of such devices approaches physical limits, new computing paradigms are emerging. Two paradigms receiving great attention are quantum and DNA-based molecular computing.

This paper focuses on DNA-based computing. This paradigm can be abstracted to growth models where computational elements called tiles are self-assembled one by one, subject to some simple hierarchical rules, to fill a given template encoding a Boolean formula. While DNA-based computational devices are known to be extremely energy efficient, little is known concerning the fundamental question of computation times. In particular, given a function, we study the time required to determine its value for a given input. In the simplest instance, the analysis has interesting connections with interacting particle systems and variational problems.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wang, H.: Proving theorems by pattern recognition, II. Bell System Technical Journal 40, 1–42 (1961)

    Google Scholar 

  2. Winfree, E.: Algorithmic Self-Assembly of DNA. PhD thesis, California Institute of Technology, Pasadena, CA (1998)

    Google Scholar 

  3. Rothemund, P., Winfree, E.: The program-size complexity of self-assembled squares. In: Proc. ACM Symp. Th. Comput., pp. 459–468 (2001)

    Google Scholar 

  4. Adleman, L., Cheng, Q., Goel, A., Huang, M.D.: Running time and program size for self-assembled squares. In: Proc. ACM Symp. Th. Comput., pp. 740–748 (2001)

    Google Scholar 

  5. Winfree, E.: Complexity of restricted and unrestricted models of molecular computation. In: Lipton, R., Baum, E. (eds.) DNA Based Computing. Am. Math. Soc., Providence, RI, pp. 199–219 (1996)

    Google Scholar 

  6. Adleman, L., Cheng, Q., Goel, A., Huang, M.D., Kempe, D., de Espanés, P.M., Rothemund, P.: Combinatorial optimization problems in self-assembly. In: Proc. ACM Symp. Th. Comput., Montreal, Canada, pp. 23–32 (2002)

    Google Scholar 

  7. Adleman, L., Cheng, Q., Goel, A., Huang, M.D., Wasserman, H.: Linear self-assemblies: Equilibria, entropy, and convergence rates. In: Elaydi, Ladas, Aulbach (eds.) New progress in difference equations. Taylor and Francis, London (to appear)

    Google Scholar 

  8. Baryshnikov, Y., Coffman, E., Winkler, P.: Linear self-assembly and random disjoint edge selection. Technical Report 03-1000, Electrical Engineering Dept., Columbia University (2004)

    Google Scholar 

  9. Baryshnikov, Y., Coffman, E., Momčilović, P.: Incremental self-assembly in the fluid limit. In: Proc. 38th Ann. Conf. Inf. Sys. Sci., Princeton, NJ (2004)

    Google Scholar 

  10. Carbone, A., Seeman, N.: Circuits and programmable self-assembling DNA structures. In: Proc. Natl. Acad. Sci., USA, vol. 99, pp. 12577–12582 (2002)

    Google Scholar 

  11. Litvinov, G., Maslov, V.: The correspondence principle for idempotent calculus and some computer applications. In: Idempotency (Bristol, 1994). Publ. Newton Inst., vol. 11, pp. 420–443. Cambridge Univ. Press, Cambridge (1998)

    Chapter  Google Scholar 

  12. Gunawardena, J.: An introduction to idempotency. In: Idempotency (Bristol, 1994). Publ. Newton Inst., vol. 11, pp. 1–49. Cambridge Univ. Press, Cambridge (1998)

    Chapter  Google Scholar 

  13. Liggett, T.: Interacting Particle Systems. Springer, New York (1985)

    MATH  Google Scholar 

  14. Liggett, T.: Stochastic Interacting Systems: Contact, Voter and Exclusion Processes. Springer, Berlin (1999)

    MATH  Google Scholar 

  15. Arnol′d, V.: Mathematical methods of classical mechanics. Graduate Texts in Mathematics, vol. 60. Springer, New York (1997); Translated from the 1974 Russian original by K. Vogtmann, A. Weinstein, Corrected reprint of the second edition (1989)

    Google Scholar 

  16. Johansson, K.: Shape fluctuations and random matrices. Comm. Math. Phys. 209, 437–476 (2000)

    Article  MATH  MathSciNet  Google Scholar 

  17. O’Connell, N.: Random matrices, non-colliding processes and queues. In: Seminaire de Probabilites XXXVI. Lecture Notes in Math., vol. 1801, pp. 165–182. Springer, Berlin (2003)

    Google Scholar 

  18. Talagrand, M.: A new look at independence. Ann. Probab. 23, 1–37 (1996)

    MathSciNet  Google Scholar 

  19. Kozlov, S.M.: The method of averaging and walks in inhomogeneous environments. Russ. Math. Surv. 40, 73–145 (1985); Translation from Usp. Mat. Nauk. 40, 61–120 (1985)

    Article  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Baryshnikov, Y., Coffman, E., Momčilović, P. (2005). DNA-Based Computation Times. In: Ferretti, C., Mauri, G., Zandron, C. (eds) DNA Computing. DNA 2004. Lecture Notes in Computer Science, vol 3384. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11493785_2

Download citation

  • DOI: https://doi.org/10.1007/11493785_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-26174-2

  • Online ISBN: 978-3-540-31844-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics