Abstract
One of the most expected applications of the human genome information is the development of genome medicine. Towards this goal, basic and applied biomedical laboratory researches and developments have been steadily in progress. However, clinical genome informatics and its applications in practice have been making slower progress compared to biomedical laboratory works. In order to facilitate the progress of clinical genome informatics and its powerful application to the development of genome medicine, the construction of the information infrastructure for genome medicine calls for urgent attention. In this paper, we propose the architecture of the information infrastructure for genome medicine. It is required to provide three essential features: security mechanisms, comprehensive information models, and intelligent analyzers. To implement these features, we employed PKI as the security mechanisms and the HL7 Version 3 as the information models. To analyze information, knowledge discovery tools are expected to be implemented in addition to a lot of clinical and genetic statistical functions.
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Nawata, H., et al.: Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13–p12 in Japanese. Journal of Human Genetics 49(11), 629–634 (2004)
Parsaye, K., Chignell, M.: Intelligent Database Tools & Applications: Hyperinformation Access, Data Quality, Visualization, Automatic Discovery. John Wiley & Sons, Inc., New York (1993)
Parsaye, K., Chingnell, M.H., Khoshafian, S., Wong, H.K.T.: Intelligent Databases: Object-Oriented, Deductive Hypermedia Technologies. John Wiley & Sons, New York (1989)
Takeda, H., et al.: Architecture for networked electronic patient record system. International Journal of Medical Informatics 60(2), 161–167 (1999)
Blobel, B.: Advanced tool kits for EPR security. Int. Journal of Medical Informatics 60(2), 169–175 (1999)
Park, Y.M., et al.: A Method to Implementing the Extended Order Communication System Using the Public Key Infrastructure (PKI) through the Patient Certification System (PCS). In: CJKMI 2001, Tokyo, Japan (2001)
Sakamoto, N.: The Construction of a Public Key Infrastructure for Healthcare Information Networks in Japan. In: Patel, V., et al. (eds.) MEDINFO 2001. IMIA, pp. 1276–1280. Amsterdam IOS Press, Amsterdam (2001)
Housley, R., et al.: Internet X.509 Public Key Infrastructure Certificate and CRL Profile. RFC 2459 (1999)
Hinchley, A.: Understanding Version 3: A primer on the HL7 Version 3 Communication Standard. Alexander Moench Publishing, Munich (2003)
Jones, T.: NPfIT interoperability - the role of HL7 version 3. HL7 UK 2003 (2003), Available at (2003), http://www.hl7.org.uk/HL7UKConferenceSite/HL7UK2003Papers.htm (Accessed December 12, 2004)
The NeCST Progress Report 2003 (2003), Available at http://secure.cihi.ca/cihiweb/en/downloads/infostand_eclaims_prog2003_e.pdf (Accessed December 12, 2004)
de Jong, T.: Medication Supply Registry Project and Demonstration in the Netherlands (2003), Available at http://www.hl7.org.uk/HL7UKConferenceSite/HL7UK2003Papers.htm (Accessed December 12, 2004)
William, B.L., Trigg, B.K.: Information System Architectures for Syndromic Surveillance. Morbidity and Mortality Weekly Report 2004 53 (Suppl.), 203–208 (2004)
The Medical Information System Development Center: The Japanese Set of Identifiers for Medical Record Information Exchange (J-MIX) (in Japanese) (2000), http://www.medis.or.jp/ (Accessed December 12, 2004)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Sakamoto, N., Nakaya, J. (2005). Towards the Construction of the Information Infrastructure for Genome Medicine. In: Shimojo, S., Ichii, S., Ling, TW., Song, KH. (eds) Web and Communication Technologies and Internet-Related Social Issues - HSI 2005. HSI 2005. Lecture Notes in Computer Science, vol 3597. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11527725_18
Download citation
DOI: https://doi.org/10.1007/11527725_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-27830-6
Online ISBN: 978-3-540-31808-8
eBook Packages: Computer ScienceComputer Science (R0)