Abstract
The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. The application of integrative approaches including theory, wet experimentation, modeling and simulation and the leveraging of a strong comparative, evolutionary framework has spawned pathosystems biology. I will show examples of how cyberinfrastructure is being developed and used to support pathosystems biology.
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References
Atkins, D., Droegemeier, K., Feldman, S., Garcia-Molina, H., Klein, M., Messerschmitt, D., Messina, P., Ostriker, J., Wright, M.: Revolutionaizing Science and Engineering Through Cyberinfrastructure: Report of the National Science Foundation Blue-Ribbon Advisory Panel on Cyberinfrastructure (2003), http://www.nsf.gov/publications/pub_summ.jsp?ods_key=cise051203
Wiener, N.: Cybernetics: or Control and Communication in the Animal and the Machine, 2nd edn., p. 212. MIT Press, Cambridge (1948)
Studholme, D.J., Downie, J.A., Preston, G.M.: Protein Domains and Architectural Innovation in Plant-Associated Proteobacteria. BMC Genomics. 6, 17 (2005)
Eubank, S., Guclu, H., Kumar, V.S., Marathe, M.V., Srinivasan, A., Toroczkai, Z., Wang, N.: Modelling Disease Outbreaks in Realistic Urban Social Networks. Nature. 429, 180–184 (2004), http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15141212
Ibid
Eckart, J.D., Sobral, B.W.: A Life Scientist’s Gateway to Distributed Data Management and Computing: The PathPort/ToolBus Framework. Omics. 7, 79–88 (2003), http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12831562
He, Y., Vines, R.R., Wattam, A.R., Abramochkin, G.V., Dickerman, A.W., Eckart, J.D., Sobral, B.W.: PIML: the Pathogen Information Markup Language. Bioinformatics (2004), http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15297293
Marks, E., Werrell, M.: Executive’s Guide to Web Services. John Wiley & Sons, Inc., Hoboken (2003)
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Sobral, B.W.S. (2005). Cyberinfrastructure for PathoSystems Biology. In: Setubal, J.C., Verjovski-Almeida, S. (eds) Advances in Bioinformatics and Computational Biology. BSB 2005. Lecture Notes in Computer Science(), vol 3594. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11532323_3
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DOI: https://doi.org/10.1007/11532323_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-28008-8
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