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Composite Module Analyst: Tool for Prediction of DNA Transcription Regulation. Testing on Simulated Data

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Advances in Natural Computation (ICNC 2005)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3611))

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Abstract

Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely organized binding of a multiplicity of spe cial proteins- transcription factors to their target sites (cis-elements) in regulatory regions of genes. Cis-element combinations provide a structural basis for the generation of unique patterns of gene expression. Here we present new method based on genetic algorithm for prediction of class-specific composite modules in promoters of functionally related or coexpressed genes and it’s testing on simulated data.

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References

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© 2005 Springer-Verlag Berlin Heidelberg

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Konovalova, T., Valeev, T., Cheremushkin, E., Kel, A. (2005). Composite Module Analyst: Tool for Prediction of DNA Transcription Regulation. Testing on Simulated Data. In: Wang, L., Chen, K., Ong, Y.S. (eds) Advances in Natural Computation. ICNC 2005. Lecture Notes in Computer Science, vol 3611. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11539117_161

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  • DOI: https://doi.org/10.1007/11539117_161

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-28325-6

  • Online ISBN: 978-3-540-31858-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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