Abstract
Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely organized binding of a multiplicity of spe cial proteins- transcription factors to their target sites (cis-elements) in regulatory regions of genes. Cis-element combinations provide a structural basis for the generation of unique patterns of gene expression. Here we present new method based on genetic algorithm for prediction of class-specific composite modules in promoters of functionally related or coexpressed genes and it’s testing on simulated data.
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© 2005 Springer-Verlag Berlin Heidelberg
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Konovalova, T., Valeev, T., Cheremushkin, E., Kel, A. (2005). Composite Module Analyst: Tool for Prediction of DNA Transcription Regulation. Testing on Simulated Data. In: Wang, L., Chen, K., Ong, Y.S. (eds) Advances in Natural Computation. ICNC 2005. Lecture Notes in Computer Science, vol 3611. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11539117_161
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DOI: https://doi.org/10.1007/11539117_161
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-28325-6
Online ISBN: 978-3-540-31858-3
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