Skip to main content

Cost-Sensitive Ensemble of Support Vector Machines for Effective Detection of Microcalcification in Breast Cancer Diagnosis

  • Conference paper
Fuzzy Systems and Knowledge Discovery (FSKD 2005)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 3614))

Included in the following conference series:

Abstract

This paper presents a new approach for the cost-sensitive classification problems based on the Boosting ensemble of support vector machines (SVMs). Different from conventional Boosting ensemble learning methods that adjust the distribution of training instances for minimizing the misclassification rate, the presented approach adjusts the training data distribution so as to minimize the expected cost of classification. This approach has been applied successfully in Microcalcification (MC) detection which is a typical cost-sensitive classification problem in breast cancer diagnosis. Its performance is evaluated by means of Receiver Operating Characteristics (ROC) curves and the expected costs of classification. Experimental results have consistently confirmed that the ROC of the SVM ensemble classifier is very close to the curve enveloping the base classifier ROC curves. This characteristic illustrates that the SVM ensemble is able to always improve the performance of the classification. Furthermore, the experimental results demonstrate that the method presented is able to not only increase the area under the ROC curve (AUC) but also minimize the expected classification cost.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dietterich, T.G.: Ensemble Methods in Machine Learning. In: First International Workshop on Multiple Classifier Systems, pp. 1–15. Springer, Heidelberg (2000)

    Chapter  Google Scholar 

  2. Margineantu, D., Dietterich, T.G.: Bootstrap Methods for the Cost-Sensitive Evaluation of Classifiers. In: ICML 2000, pp. 583–590 (2000)

    Google Scholar 

  3. Drummond, C., Holte, R.C.: Exploiting the Cost (In)sensitivity of Decision Tree Splitting Criteria. In: ICML 2000, pp. 239–246 (2000)

    Google Scholar 

  4. Ting, K.M.: A Comparative Study of Cost-Sensitive Boosting Algorithms. In: ICML 2000, pp. 983–990 (2000)

    Google Scholar 

  5. Kim, H.C., Pang, S., et al.: Pattern Classification Using Support Vector Machine Ensemble. In: ICPR 2002, pp. 20160–20163 (2002)

    Google Scholar 

  6. Kim, H.C., Peng, S., et al.: Constructing Supporting Vector Machine Ensemble. The Journal of Pattern Recognition 36, 2757–2767 (2003)

    Article  MATH  Google Scholar 

  7. Buciu, I., Kotropoulos, C., Pitas, I.: Combining Support Vector Machines for Accurate Face Detection. In: Proc. of ICIP 2001, pp. 1054–1057 (2001)

    Google Scholar 

  8. Valentini, G., Dietterich, T.G.: Bias-variance analysis of Support Vector Machines for the Development of SVM-based Ensemble Methods. Journal of Machine Learning Research 5, 725–775 (2004)

    MathSciNet  Google Scholar 

  9. Antonie, M.L., Zaiane, O.R., Coman, A.: Application of Data Mining Techniques for Medical Image Classification. In: MDM/KDD 2001 with ACM SIGKDD (2001)

    Google Scholar 

  10. Yu, S., Guan, L.: A CAD System for the Automatic Detection of Clustered Microcalcifications in Digitized Mammogram Films. IEEE Trans. Med. Imag. 19, 115–126 (2000)

    Article  Google Scholar 

  11. Sajda, P., Spence, C., Pearson, J.: Learning Contextual Relationships in Mammograms Using a Hierarchical Pyramid Neural Network. IEEE Trans. Med. Imag. 21(3), 239–250 (2002)

    Article  Google Scholar 

  12. El-Naqa, I., Yang, Y., Wernick, M.N., et al.: A Support Vector Machine Approach for Detection of Microcalcifications. IEEE Trans. Med. Imag. 21(12), 1552–1563 (2002)

    Article  Google Scholar 

  13. Ordonez, C., Santana, C., et al.: Discovering Interesting Association Rules in Medical Data. In: ACM SIGMOD Workshop on Research Issues in Data Mining and Knowledge Discovery (2000)

    Google Scholar 

  14. Zaiane, O.R., Antonie, M.L., Coman, A.: Mammography Classification by an Association Rule-based Classifier. In: MDM/KDD 2002 with ACM SIGKDD (2002)

    Google Scholar 

  15. Freund, Y., Schapire, R.E.: A Decision-theoretic Generalization of On-line Learning and an Application to Boosting. Journal of Computer and System Sciences 55(1), 119–139 (1997)

    Article  MATH  MathSciNet  Google Scholar 

  16. Schapire, R.E.: A brief introduction to Boosting. In: The 16th International Joint Conference on Artificial Intelligence, pp. 1401–1406 (1999)

    Google Scholar 

  17. Elkan, C.: The Foundations of Cost-Sensitive Learning. In: The 17th International Joint Conference on Artificial Intelligence, IJCAI 2001, pp. 973–978 (2001)

    Google Scholar 

  18. Ting, K.M., Zheng, Z.: Boosting Cost-Sensitive Trees. In: The First International Conference on Discovery Science, pp. 244–255 (1998)

    Google Scholar 

  19. Fan, W., Stolfo, S., et al.: Adacost: Misclassification Cost-sensitive Boosting. In: ICML 1999, pp. 99–105 (1999)

    Google Scholar 

  20. Provost, F., Fawcett, T.: Robust Classification for Imprecise Environments. Machine Learning Journal 42(3), 203–231 (2001)

    Article  MATH  Google Scholar 

  21. Fawcett, T.: ROC Graphs: Notes and Practical Considerations for Researchers. Submitted to Machine Learning Journal (2004)

    Google Scholar 

  22. Bradley, A.P.: The use of the Area under the ROC curve in the Evaluation of Machine Learning Algorithms. The Journal of Pattern Recognition 30(7), 1145–1159 (1997)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Peng, Y., Huang, Q., Jiang, P., Jiang, J. (2005). Cost-Sensitive Ensemble of Support Vector Machines for Effective Detection of Microcalcification in Breast Cancer Diagnosis. In: Wang, L., Jin, Y. (eds) Fuzzy Systems and Knowledge Discovery. FSKD 2005. Lecture Notes in Computer Science(), vol 3614. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11540007_59

Download citation

  • DOI: https://doi.org/10.1007/11540007_59

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-28331-7

  • Online ISBN: 978-3-540-31828-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics