Abstract
In this work, an integrated Web-based model integrating a number of components has been proposed to analyze, manage and retrieve biological information. In particular, we deal with Expressed Sequence Tags (EST) data that is an important resource for gene identification, genome annotation and comparative genomics. A high-performance and user-friendly three-tier Web application consisting of EST modeling and database (ESTMD) has been developed to facilitate the retrieval and analysis of EST information. It provides a variety of Web services and tools for searching raw, cleaned and assembled EST sequences, genes and Gene Ontology, as well as pathway information. It can be accessed at http://129.130.115.72:8080/estweb/index.html.
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Mao, C., Cushman, J.C., May, G.D., Weller, J.W.: ESTAP-An Automated System for the Analysis of EST Data. Bioinformatics 19, 1720–1722 (2003)
Everitt, R., Minnema, S.E., Wride, M.A., Koster, C.S., Hance, J.E., Mansergh, F.C., Rancourt, D.E.: RED: The Analysis, Management and Dissemination of Expressed Sequence Tags. Bioinformatics 18, 1692–1693 (2002)
Kumar, C.G., Le Duc, R., Gong, G., Roinishivili, L., Lewin, H.A., Liu, L.: ESTIMA, a tool for EST management in a multi-project environment. BMC. Bioinformatics 5, 176 (2004)
Christoffels, A., van, G.A., Greyling, G., Miller, R., Hide, T., Hide, W.: STACK: Sequence Tag Alignment and Consensus Knowledgebase. Nucleic Acids Res. 29, 234–238 (2001)
Paquola, A.C., Nishyiama Jr., M.Y., Reis, E.M., da Silva, A.M., Verjovski-Almeida, S.: ESTWeb: bioinformatics services for EST sequencing projects. Bioinformatics 19, 1587–1588 (2003)
Ayoubi, P., Jin, X., Leite, S., Liu, X., Martajaja, J., Abduraham, A., Wan, Q., Yan, W., Misawa, E., Prade, R.A.: PipeOnline 2.0: automated EST processing and functional data sorting. Nucleic Acids Res. 30, 4761–4769 (2002)
Ashburner, M., Ball, C.A., Blake, J.A., Botstein, D., Butler, H., Cherry, J.M., Davis, A.P., Dolinski, K., Dwight, S.S., Eppig, J.T., Harris, M.A., Hill, D.P., Issel-Tarver, L., Kasarskis, A., Lewis, S., Matese, J.C., Richardson, J.E., Ringwald, M., Rubin, G.M., Sherlock, G.: Gene Ontology: Tool for the Unification of Biology. The Gene Ontology Consortium. Nature Genet. 25, 25–29 (2000)
Gene Ontology Consortium. Creating the Gene Ontology Resource: Design and Implementation. Genome Res. 11, 1425–1433 (2001)
Ogata, H., Goto, S., Sato, K., Fujibuchi, W., Bono, H., Kanehisa, M.: KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 27, 29–34 (1999)
Altschul, S.F., Gish, W., Miller, W., Myers, E.W., Lipman, D.J.: Basic Local Alignment Search Tool. J. Mol. Biol. 215, 403–410 (1990)
Fly Base Consortium. The Fly Base Database of the Drosophila Genome Projects and Community Literature. Nucleic Acids Res. 31, 172–175 (2003)
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© 2006 Springer-Verlag Berlin Heidelberg
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Deng, Y., Dong, Y., Brown, S.J., Zhang, C. (2006). An Integrated Web-Based Model for Management, Analysis and Retrieval of EST Biological Information. In: Shen, H.T., Li, J., Li, M., Ni, J., Wang, W. (eds) Advanced Web and Network Technologies, and Applications. APWeb 2006. Lecture Notes in Computer Science, vol 3842. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11610496_129
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DOI: https://doi.org/10.1007/11610496_129
Publisher Name: Springer, Berlin, Heidelberg
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