Abstract
Over a period of several years we apply the systems biology approach to investigate the dynamic regulatory mechanisms controlling the expression of segmentation genes in Drosophila embryo. Due to ongoing data acquisition, development of new processing and analysis methods, as well as modification and improvement of old ones serious problems arose with data and workflows management. Different geographical location of research groups poses additional difficulties. To solve these problems we have developed an information management system using multiagent and REST architectures. This system is easily extendable to deal with new data processing and analysis methods, flexible in specification and modification of these methods, scalable and supports distributed processing and analysis of data.
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References
Stevens, R.D., Robinson, A.J., Goble, C.A.: Mygrid: personalised bioinformatics on the information grid. Bioinformatics 19, 302–304 (2003)
Oinn, T., Addis, M., Ferris, J., Marvin, D., Senger, M., Greenwood, M., Carver, T., Glover, K., Pocock, M.R., Wipat, A., Li, P.: Taverna: a tool for the composition and enactment of bioinformatics workflows. Bioinformatics 20, 3045–3054 (2004)
Wilkinson, M., Schoof, H., Ernst, R., Haase, D.: Biomoby successfully integrates distributed heterogeneous bioinformatics web services. The planet exemplar case. Plant Physiology 138, 5–17 (2005)
Senger, M., Rice, P., Oinn, T.: Soaplab - a unified sesame door to analysis tools. In: Proceedings of the UK eScience All Hands Meeting, pp. 509–513 (2003)
Fielding, R.T.: Architectural styles and the design of network-based software architectures. Doctoral dissertation (2000)
Myasnikova, E., Samsonova, A., Kozlov, K., Samsonova, M., Reinitz, J.: Registration of the expression patterns of drosophila segmentation genes by two independent methods. Bioinformatics 17, 3–12 (2001)
Jaeger, J., Surkova, S., Blagov, M., Janssens, H., Kosman, D., Kozlov, K.N., Manu, M.E., Vanario-Alonso, C.E., Samsonova, M., Sharp, D.H., Reinitz, J.: Dynamic control of positional information in the early drosophila embryo. Nature 430, 368–371 (2004)
Foe, V.E., Alberts, B.M.: Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in drosophila embryogenesis. The Journal of Cell Science 61, 31–70 (1983)
Ingham, P.W.: The molecular genetics of embryonic pattern formation in drosophila. Nature 335, 25–34 (1988)
Jaeger, J., Blagov, M., Kosman, D., Kozlov, K.N., Manu, M.E., Surkova, S., Vanario-Alonso, C.E., Samsonova, M., Sharp, D.H., Reinitz, J.: Dynamical analysis of regulatory interactions in the gap gene system of drosophila melanogaster. Genetics 167, 1721–1737 (2004)
Genesereth, M., Ketchpel, S.: Software agents. Communications of the ACM 37(7), 48–53 (1994)
Poustelnikova, E., Pisarev, A., Blagov, M., Samsonova, M., Reinitz, J.: A database for management of gene expression data in situ. Bioinformatics 20, 2212–2221 (2004)
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Samsonova, M., Pisarev, A., Kozlov, K., Poustelnikova, E., Tkachenko, A. (2006). An Information Management System for Collaboration Within Distributed Working Environment. In: Leser, U., Naumann, F., Eckman, B. (eds) Data Integration in the Life Sciences. DILS 2006. Lecture Notes in Computer Science(), vol 4075. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11799511_18
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DOI: https://doi.org/10.1007/11799511_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36593-8
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