Abstract
There is currently a great interest in using single-nucleotide polymorphisms (SNPs) in genetic linkage and association studies because of the abundance of SNPs as well as the availability of high-throughput genotyping technologies. Here, we apply a novel ensemble decision approach to extract the relevant SNPs for alcoholism using sib-pair IBD profiles of pedigrees. The results indicate that ensemble decision tree is a promising algorithm for mining genetic markers for complex genetic diseases.
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Jiang, Y. et al. (2006). Analysis of Sib-Pair IBD Profiles Using Ensemble Decision Tree Approach: Application to Alcoholism. In: Huang, DS., Li, K., Irwin, G.W. (eds) Computational Intelligence and Bioinformatics. ICIC 2006. Lecture Notes in Computer Science(), vol 4115. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11816102_82
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DOI: https://doi.org/10.1007/11816102_82
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-37277-6
Online ISBN: 978-3-540-37282-0
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