Abstract
We present a new spot lesion detection algorithm for retinal images with background diabetic retinopathy (DR) pathologies. The highlight of this algorithm is its capability to deal with all DR-related spot lesions of various sizes and shapes that is accomplished by a unique adaptive multiscale morphological processing technique. A scale map is generated to delineate lesion areas based an edge model, and it is used to fuse multiscale morphological processing results for lesion enhancements. The local/releative entropy thresholding techniques are employed to segment lesion regions, and a scale-guided validation process is used to remove over-detections based on the scale map. The proposed algorithm is tested on 30 retinal images where all spot lesions are hand-labelled for performance evaluation. Compared with two existing algorithms, the proposed one significantly improves the overall performance of spot lesion detection producing higher sensitivity and/or predictive values.
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
ETDRS Research Group: Grading dabetic retinopathy from seteoscopic color fundus photographos – an extension of the modified Airelie House Classification (ETDRS report number 10). Ophthalmology 98, 786–806 (1991)
Fransen, S.R., Leonard-Martin, T.C., Feuer, W.J., Hildebrand, P.L.: Clinical evaluation of patients with diabetic retinopathy: Accuracy of the Inoveon diabetic retinopathy-3DT system. The American Academy of Ophthalmology 109, 595–601 (2002)
Spencer, T., Olson, J.A., McHardy, K.C., Sharp, P.F., Forrester, J.V.: An image-processing strategy for the segmentation and quantification of microaneurysms in fluorescein angiograms of the ocular fundus. Computers and Biomedical Research 29, 284–302 (1996)
Niemeijer, M., Ginneken, B.V., Staal, J., Suttorp-Schulten, M.S.A., Abramoff, M.D.: Automatic detection of red lesions in digital color fundus photographs. IEEE Trans. Medical Imaging 24, 584–592 (2005)
Frame, A.J., Undrill, P.E., Cree, M.J., Olson, J.A., McHardy, K.C., Sharp, P.F., Forrester, J.V.: A comparison of computer based classification methods applied to the detection of microaneurysms in ophthalmic fluorescein angiograms. Computers in Biology and Medicine, 225–238 (1998)
Walter, T., Klein, J.C., Massin, P., Erginary, A.: A contribution of image processing to the diagnosis of diabetic retinopathy–detection of exudates in color fundus images of the human retina. IEEE Trans. Medical Imaging 21, 1236–1243 (2001)
Sbeh, A.B., Cohen, L.D., Mimoum, G., Coscas, G.: A new approach of geodesic reconstruction for drusen segmentation in eye fundus images. IEEE Tran. Medical Imaging 20, 1321–1333 (2001)
Zhang, X., Chutatape, O.: Top-down and bottom-up strategies in lesion detection of background diabetic retinopathy. In: Proc. IEEE Conference on Computer Vision and Pattern Recognition, vol. 2, pp. 422–428 (2005)
Maragos, P.: Pattern spectrum and multiscale shape representation. IEEE Trans. Pattern Analysis and Machine Intelligence 11, 701–716 (1989)
Vincent, L.: Morphological grayscale reconstruction: Definition, efficient algorithms and applications in image analysis. In: Proc. IEEE Conference on Computer Vision and Pattern Recognition, pp. 633–635 (1992)
Mukhopadhyay, S., Chanda, B.: An edge preserving noise smoothing technique using multiscale morphology. Signal Processing, 527–544 (2002)
vanBeck, P.J.L.: Edge-Based Image Representation and Coding. PhD thesis, Delft University of Technology, the Netherlands (1995)
Fan, G., Cham, W.K.: Model-based edge reconstruction for low bit-rate wavelet-compressed images. IEEE Trans. Circuits and Systems for Video Technology 10, 120–132 (2000)
Pal, N.R., Pal, S.K.: Entropic thresholding. Signal Processing 16, 97–108 (1989)
Chang, C.I., Chen, K., Wang, J., Althouse, M.L.G.: A relative entropy-based approach to image thresholding. Pattern Recognition 27, 1275–1289 (1994)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zhang, X., Fan, G. (2006). Retinal Spot Lesion Detection Using Adaptive Multiscale Morphological Processing. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2006. Lecture Notes in Computer Science, vol 4292. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11919629_50
Download citation
DOI: https://doi.org/10.1007/11919629_50
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-48626-8
Online ISBN: 978-3-540-48627-5
eBook Packages: Computer ScienceComputer Science (R0)