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Parallel CLUSTAL W for PC Clusters

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Computational Science and Its Applications — ICCSA 2003 (ICCSA 2003)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2668))

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Abstract

This paper presents a parallel version of CLUSTALW, called pCLUSTAL. In contrast to the commercial SGI parallel Clustal, which requires an expensive shared memory SGI multiprocessor, pCLUSTAL can be run on a range of distributed and shared memory parallel machines, from high-end parallel multiprocessors (e.g. Sunfire 6800, IBM SP2, etc.) to PC clusters, to simple networks of workstations. We have implemented pCLUSTAL using C and the MPI communication library, and tested it on a PC cluster. Our experimental evaluation shows that our pCLUSTAL code achieves similar or better speedup on a distributed memory PC clusters than the commercial SGI parallel Clustal on a shared memory SGI multiprocessor.

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References

  1. H. Carillo. and D. Lipman. The multiple sequence alignment problem in biology. SIAM J. Appl. Math, 48(5):1073–1082, 1998.

    Article  Google Scholar 

  2. G.H. Gonnet, C. Korostensky, and S. Benner. Evaluation measures of multiple sequence alignments. J Comput Biol., 7(1–2):261–276, 2000.

    Article  Google Scholar 

  3. H.G. Higgins, A.J. Bleasby, and R. Fuchs. CLUSTAL V: improved software for multiple sequence alignment. CABIOS, 8:189–191, 1992.

    Google Scholar 

  4. H.G. Higgins and P.M. Sharp. CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. Gene, 73:237–244, 1988.

    Article  Google Scholar 

  5. H.G. Higgins and P.M. Sharp. Fast and sensitive multiple sequence alignments on a microcomputer. CABIOS, 5:151–153, 1989.

    Google Scholar 

  6. H.G. Higgins, J.D. Thompson, and T.J. Gibson. Using CLUSTAL for multiple sequence alignments. Methods Enzymol, 266:383–402, 1996.

    Article  Google Scholar 

  7. F. Jeanmougin, J.D. Thompson, M. Gouy, D.G. Higgins, and T.J. Gibson. Multiple sequence alignment with CLUSTAL X. Trends Biochem Sci, 23:403–405, 1998.

    Article  Google Scholar 

  8. Performance optimization of clustal w: Parallel clustal w, ht clustal, and multiclustal. http://www.sgi.com/ industries/sciences/chembio/resources/papers/Clustal_DevNews/Clustal_DevNews.html.

  9. J.D. Thompson, T.J. Gibson, F. Plewniak, F. Jeanmougin, and H.G. Higgins. The CLUSTAL X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Research, 24:4876–4882, 1997.

    Article  Google Scholar 

  10. J.D. Thompson, H.G. Higgins, and T.J. Gibson. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Research, 22:4673–4680, 1994.

    Article  Google Scholar 

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© 2003 Springer-Verlag Berlin Heidelberg

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Cheetham, J., Dehne, F., Pitre, S., Rau-Chaplin, A., Taillon, P.J. (2003). Parallel CLUSTAL W for PC Clusters. In: Kumar, V., Gavrilova, M.L., Tan, C.J.K., L’Ecuyer, P. (eds) Computational Science and Its Applications — ICCSA 2003. ICCSA 2003. Lecture Notes in Computer Science, vol 2668. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-44843-8_32

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  • DOI: https://doi.org/10.1007/3-540-44843-8_32

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40161-2

  • Online ISBN: 978-3-540-44843-3

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