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Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulating Regional Deformation

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Functional Imaging and Modeling of the Heart (FIMH 2001)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2230))

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Abstract

We present a one-dimensional mathematical model to explain changes in regional radial myocardial deformation during ischaemia. The model makes use of cellular contraction properties of normal and ischaemic myocytes extracted from an animal model of induced chronic, regional ischaemia of the posterior wall. Simulations of the model are compared to the deformation patterns observed in the experimental animal models of regional ischaemia.

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References

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Author information

Authors and Affiliations

  1. Department of Cardiology, K.U. Leuven, University Hospitals Gasthuisberg, Herestraat 49, B-3000, Leuven, Belgium

    Piet Claus, Bart Bijnens, Frank Weidemann, Christoph Dommke, Virginie Bito, Frank Heinzel, Karin Sipido, Ivan De Scheerder, Frank E. Rademakers & George R. Sutherland

Authors
  1. Piet Claus
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  2. Bart Bijnens
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  3. Frank Weidemann
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  4. Christoph Dommke
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  5. Virginie Bito
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  6. Frank Heinzel
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  7. Karin Sipido
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  8. Ivan De Scheerder
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  9. Frank E. Rademakers
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  10. George R. Sutherland
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Editor information

Editors and Affiliations

  1. Helsinki University of Technology, Institute of Biomedical Engineering, P.O.Box 2200, 02015, Finland

    Toivo Katila  & Jukka Nenonen  & 

  2. bâtiment Blaise Pascal, CREATIS, CNRS, INSA, 20, boulevard Albert Einstein, 69621, Villeurbanne cedex, France

    Isabelle E. Magnin , Patrick Clarysse  & Johan Montagnat ,  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Claus, P. et al. (2001). Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulating Regional Deformation. In: Katila, T., Nenonen, J., Magnin, I.E., Clarysse, P., Montagnat, J. (eds) Functional Imaging and Modeling of the Heart. FIMH 2001. Lecture Notes in Computer Science, vol 2230. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45572-8_19

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  • DOI: https://doi.org/10.1007/3-540-45572-8_19

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42861-9

  • Online ISBN: 978-3-540-45572-1

  • eBook Packages: Springer Book Archive

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