Abstract
Dynamic microscopy of the nailfold capillaries using Na- fluorescein dye can be used to assess the condition of the peripheral circulation of Scleroderma patients, yielding more information than simple morphological studies. In this paper we describe a computer based system for this kind of study and present preliminary results on Scleroderma patients. We show how the dye concentrations vary both in time and as a function of distance from the capillary wall in unprecedented resolution, suggesting that a simple permeability model may be applicable to the data.
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© 2001 Springer-Verlag Berlin Heidelberg
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Allen, P.D., Taylor, C.J., Herrick, A.L., Anderson, M., Moore, T. (2001). Microvascular Dynamics in the Nailfolds of Scleroderma Patients Studied Using Na-Fluorescein dye. In: Insana, M.F., Leahy, R.M. (eds) Information Processing in Medical Imaging. IPMI 2001. Lecture Notes in Computer Science, vol 2082. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45729-1_21
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DOI: https://doi.org/10.1007/3-540-45729-1_21
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