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Estimability of Spatio-Temporal Activation in fMRI

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Information Processing in Medical Imaging (IPMI 2001)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2082))

Abstract

Event-related functional magnetic resonance imaging (fMRI) is considered as an estimation and reconstruction problem. A linear model of the fMRI system based on the Fourier sampler (k-space) approximation is introduced and used to examine what parameters of the activation are estimable, i.e. can be accurately reconstructed in the noisefree limit. Several possible spatio-temporal representations of the activation are decomposed into null and measurement components. A causal representation of the activation using generalized Laguerre polynomials is introduced.

Acknowledgements

We thank Angel Pineda for valuable discussions. This work was supported by NIH grants R01 CA52643 and P41 RR14304. A.L. was supported by NSF grant VIGRE 9977116.

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Author information

Authors and Affiliations

  1. Center for Gamma-Ray Imaging, University of Arizona, Tucson, AZ, 85721, USA

    Andre Lehovich, Harrison H. Barrett & Eric W. Clarkson

  2. Department of Radiology, USA

    Andre Lehovich, Harrison H. Barrett, Eric W. Clarkson & Arthur F. Gmitro

  3. Program in Applied Mathematics, University of Arizona, USA

    Andre Lehovich, Harrison H. Barrett & Eric W. Clarkson

  4. Optical Sciences Center, Optical Sciences Center, USA

    Harrison H. Barrett, Eric W. Clarkson & Arthur F. Gmitro

Authors
  1. Andre Lehovich
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  2. Harrison H. Barrett
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  3. Eric W. Clarkson
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  4. Arthur F. Gmitro
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Editor information

Editors and Affiliations

  1. Biomedical Engineering, University of California, One Shields Avenue, Davis, CA, 95616, USA

    Michael F. Insana

  2. Signal and Image Processing Institute, University of Southern California, 3740 McClintock Avenue, Los Angeles, CA, 90089-2564, USA

    Richard M. Leahy

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© 2001 Springer-Verlag Berlin Heidelberg

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Lehovich, A., Barrett, H.H., Clarkson, E.W., Gmitro, A.F. (2001). Estimability of Spatio-Temporal Activation in fMRI. In: Insana, M.F., Leahy, R.M. (eds) Information Processing in Medical Imaging. IPMI 2001. Lecture Notes in Computer Science, vol 2082. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45729-1_28

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  • DOI: https://doi.org/10.1007/3-540-45729-1_28

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42245-7

  • Online ISBN: 978-3-540-45729-9

  • eBook Packages: Springer Book Archive

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