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Matching of Spots in 2D Electrophoresis Images. Point Matching Under Non-uniform Distortions

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Combinatorial Pattern Matching (CPM 1999)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1645))

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Abstract

In this paper, we study pattern matching of points under non-uniform distortions. First we give a natural definition for the problem. Next we present a simple polynomial time algorithm for the one-dimensional case of the problem, whereas we prove that it is NP-hard in two (or more) dimensions. Then we present a practical heuristic algorithm for finding a matching between two sets of spots obtained by the two-dimensional gel electrophoresis technique, which is a special but important case of the problem.

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Author information

Authors and Affiliations

  1. Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai Minato-ku, Tokyo, 108-8639, Japan

    Tatsuya Akutsu

  2. Department of Bioscience Systems, Mitsui Knowledge Industry Co., Ltd., 2-7-14 Higashinakano, Nakano-ku, Tokyo, 164-8555, Japan

    Kyotetsu Kanaya & Akira Ohyama

  3. National Institute of Genetics, 1111 Yata, Mishima-city, Shizuoka, 411-8540, Japan

    Asao Fujiyama

Authors
  1. Tatsuya Akutsu
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  2. Kyotetsu Kanaya
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  3. Akira Ohyama
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  4. Asao Fujiyama
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Editor information

Editors and Affiliations

  1. Institute Gaspard-Monge, University of Marne-la-Vallée, F 77454, Marne-la-Vallée Cedex 2, France

    Maxime Crochemore

  2. Department of Computer Science, University of Warwick, Coventry, CV4 7AL, England

    Mike Paterson

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© 1999 Springer-Verlag Berlin Heidelberg

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Akutsu, T., Kanaya, K., Ohyama, A., Fujiyama, A. (1999). Matching of Spots in 2D Electrophoresis Images. Point Matching Under Non-uniform Distortions. In: Crochemore, M., Paterson, M. (eds) Combinatorial Pattern Matching. CPM 1999. Lecture Notes in Computer Science, vol 1645. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-48452-3_16

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  • DOI: https://doi.org/10.1007/3-540-48452-3_16

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66278-5

  • Online ISBN: 978-3-540-48452-3

  • eBook Packages: Springer Book Archive

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