Abstract
Ultrasonic techniques are presented for the study of soft biological tissue structure and function. Changes in echo waveforms caused by microscopic variations in the elastic properties of tissue can reveal disease mechanism, in vivo. On a larger scale, elasticity imaging describes the macroscopic elastic properties of soft tissues. We present an analysis framework and preliminary results for studying disease-induced changes in soft tissue using these two acoustic techniques to investigate structural changes at different scales.
Preview
Unable to display preview. Download preview PDF.
References
M.F. Insana, and D.G. Brown, “Acoustic Scattering Theory Applied to Soft Biological Tissues,” in Ultrasonic Scattering in Biological Tissues, edited by K.K. Shung and G.A. Thieme, CRC Press, Boca Raton, pp. 75–124, 1993.
E.J. Feleppa, F.L. Lizzi, D.J. Coleman, and M.M. Yaremko, “Diagnostic spectrum analysis in ophthalmology: a physical perspective,” Ultrasound Med. Biol, vol. 12, pp. 623–631, 1986.
J.E. Perez, J.G. Miller, M.R. Holland, S.A. Wickline, A.D. Waggoner, B. Barzilai, and B.E. Sobel, “Ultrasonic tissue characterization: integrated backscatter imaging for detecting myocardial structural properties and on-line quantitation of cardiac function,” Am. J. Card. Imaging, vol. 8, pp. 106–112, 1994.
M.F. Insana, J.G. Wood, and T.J. Hall, “Identifying acoustic scattering sources in normal renal parenchyma in vivo by varying arterial and ureteral pressures,” Ultrasound Med. Biol., vol. 18, pp. 587–599, 1992.
J. Ophir, I. Cespedes, H. Ponnekanti, Y. Yazdi, and X. Li, “Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissue,” Ultrason. Imaging, vol. 13, pp. 111–134, 1991.
K.J. Parker, S.R. Huang, R.A. Muslin, R.M. Lerner, “Tissue Response to Mechanical Vibrations for Sonoelasticity Imaging,” Ultrasound Med. Biol., vol. 16, pp. 241–246, 1990.
R. Muthupillai, D.J. Lomas, P.J. Rossman, J.F. Greenleaf, A. Manduca, R.L. Ehman, “Magnetic Resonance Elastography by Direct Visualization of Propagating Acoustic Strain Waves,” Science, vol. 269, pp. 1789–1936, 1995.
M. Tristan, D.C. Barbosa, D.O. Cosgrove, D.K. Nassiri, J.C. Bamber, and C.R. Hill, “Ultrasonic Study of In Vivo Kinetic Characteristics of Human Tissues,” Ultrasound Med. Biol., vol. 12, pp. 927–937, 1986.
A.P. Sarvazyan, A.R. Skovoroda, S.Y. Emelianov, J.B. Fowlkes, J.G. Pipe, R.S. Adler, R.B. Buxton, P.L. Carson, “Biophysical Bases of Elasticity Imaging,” Acoustical Imaging, vol. 21, pp. 223–240, 1995.
A. Viidik, “Mechanical Properties of Parallel-fibered Collagenous Tissue,” (Chapter 17, pp. 237–255) and “Interdependence between Structure and Function in Collagenous Tissues,” (Chapter 18, pp. 257–280), in Biology of Collagen, edited by A. Viidik and J. Vuust, Academic Press, New York, 1980.
P. Chaturvedi, and M.F. Insana, “A Generalized Acoustic Backscatter Model with Implications on Tissue Characterization,” under preparation, 1997.
Y.C. Fung, A First Course in Continuum Mechanics, second ed., Prentice Hall, Englewood Cliffs, NJ, 1977.
M.F. Insana, and T.J. Hall, “Parametric ultrasound imaging from backscatter coefficient measurements: image formation and interpretation,” Ultrasonic Imaging, vol. 12, pp. 245–267, 1990.
J.A. Campbell, and R.C. Waag, “Ultrasonic Scattering Properties of Three Random Media with Implications for Tissue Characterization,” J. Acoust. Soc. Am. vol. 75, pp. 1879–1886, 1984.
J.F. Chen, and J.A. Zagzebski, “Frequency Dependence of Backscatter Coefficient Versus Scatterer Volume Fraction,” IEEE Trans. Ultrason., Ferroelec., Freq. Control, vol. 43, pp. 345–353, 1996.
P. Chaturvedi and M.F. Insana, “Bayesian and Least Squares Approaches to Ultrasonic Scatterer Size Image Formation,” IEEE Trans. Ultrason., Ferroelect., Freq. Contrl., vol. 44, no. 1, 1997.
P. Chaturvedi, and M.F. Insana, “A Mathematical Model for Progression of Renal Diseases,” J. Theor. Biol., in print, 1997.
M. Bilgen, and M. F. Insana, “Deformation Models and Correlation Analysis in Elastography,” J. Acoust. Soc. Am., vol. 99, pp. 3212–3224, 1996.
L.N. Bohs, and G.E. Trahey, “A Novel Method for Angle Independent Ultrasonic Imaging of Blood Flow and Tissue Motion,” IEEE Trans. Biomed. Imaging, vol. 38, pp. 280–286, 1991.
Y. Yoshida, T. Kawamura, M. Ikoma, A. Fogo, and I. Ichikawa, “Effects of antihypertensive drugs on glomerular morphology,” Kidney Int., vol. 36, pp. 626–635, 1989.
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 1997 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Chaturvedi, P., Insana, M.F., Hall, T.J. (1997). Acoustic and elastic imaging to model disease-induced changes in soft tissue structure. In: Duncan, J., Gindi, G. (eds) Information Processing in Medical Imaging. IPMI 1997. Lecture Notes in Computer Science, vol 1230. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-63046-5_4
Download citation
DOI: https://doi.org/10.1007/3-540-63046-5_4
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-63046-3
Online ISBN: 978-3-540-69070-2
eBook Packages: Springer Book Archive