Abstract
Medical image processing technique provides an objective and quantitative approach for characterizing the pathological tissue images. In this paper, the fractal dimension was used to quantify the image textures for differentiating the normal and cancerous cells in the liver tissue image. Several image enhancement methods and one edge detection method were applied for accentuating the objects of interest before fractal dimension estimation. From the results, it is shown that the edge-based histogram equalization would be the best one among all these image enhancement methods. In addition, any two fractal dimensions were combined as the input features to the learning vector quantization network for tissue classification. From the results obtained from ten normal and ten cancer cases, the accuracy was demonstrated to be more than 90%. Above all, the user-friendly graphical user interface was also developed in this study.
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References
Public Health in Taiwan Area, Department of Health, The Executive Yuan, ROC, March 1995.
Erler BS, Troung HM, Kim SS, Huh MH, Geller SA, Marchevsky AM. A study of hepatocellular carcinoma using morphometric and densitometric image analysis. Am J Clin Pathol 1993; 100:151–157
Dougherty G. Quantitative indices for ranking the severity of hepatocellular carcinoma. Comput Med Imag & Graph 1995; 19:329–338
Thiran JP, Macq B. Morphological feature extraction for the classification of digital images of cancerous tissues. IEEE Trans Biomed Eng 1996; 43:1011–1020
Chow NH, Hsu PI, Lin XZ, et al. Expression of vascular endothelial growth factor (VEGF) in normal liver and hepatocellular carcinomas-An immunohistochemical study. Human Path 1997; 28:698–703
Otsu N. A threshold selection method from gray-level histogram. IEEE Trans Syst Man Cybern 1979; 9:115–120
Leu L. Image contrast enhancement based on the intensities of edge pixels. CVGIP: Graph Models and Image Proc 1992; 54:497–506
Negrate AL, Beghdadi A, Dupoisot H. An image enhancement technique and its evaluation through bimodality analysis. CVGIP: Graph Models and Image Proc 1992; 54: 13–22
Sarkar N, Chaudhuri BB. An efficient differential box-counting approach to compute fractal dimensions of image. IEEE Trans Syst Man Cybern 1994; 24:115–120
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© 2000 Springer-Verlag London
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Cheng, KS., Sun, R., Chow, NH. (2000). Cancerous Liver Tissue Differentiation Using LVQ. In: Malmgren, H., Borga, M., Niklasson, L. (eds) Artificial Neural Networks in Medicine and Biology. Perspectives in Neural Computing. Springer, London. https://doi.org/10.1007/978-1-4471-0513-8_9
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DOI: https://doi.org/10.1007/978-1-4471-0513-8_9
Publisher Name: Springer, London
Print ISBN: 978-1-85233-289-1
Online ISBN: 978-1-4471-0513-8
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