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Stimulus-Specific Adaptation, Models

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Encyclopedia of Computational Neuroscience

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Definition

Stimulus-specific adaptation (SSA) refers to a reduction in neural activity due to the repeated presentation of a stimulus, which does not generalize to other stimuli (Ulanovsky et al. 2003). SSA is present in auditory cortex (Ulanovsky et al. 2003), thalamus (Antunes et al. 2010), and inferior colliculus (IC) (Malmierca et al. 2009), but not the cochlear nucleus (Ayala et al. 2013). SSA has attracted interest on account of its similarity to mismatch negativity (MMN) in human auditory evoked potentials (Nelken and Ulanovsky 2007; cf. Farley et al. 2010). Computer models of SSA aim to capture the main features of single and multiunit responses to sequences of stimuli containing rare, or novel, events.

Detailed Description

Measuring SSA

Several methods exist for measuring SSA. In the simplest case, one can measure the effect of one or more conditioner tones on the neural response to a probe tone with respect to some feature, e.g., frequency (Fig. 1a). Other studies measure...

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References

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Authors and Affiliations

  1. MRC Institute of Hearing Research, NG7 2RD, Nottingham, UK

    Robert Mill

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  1. Robert Mill
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Correspondence to Robert Mill .

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Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Mill, R. (2014). Stimulus-Specific Adaptation, Models. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_109-2

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_109-2

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  • Online ISBN: 978-1-4614-7320-6

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