Synonyms
Definition
Neuronal parameter co-regulation is the exploration or alteration of distinct subsets of parameters (e.g., synaptic or membrane conductances) and how these parameters act in concert leading to changes in, or conservation of, neuronal output.
Detailed Description
The underlying ionic conductances found within a model neuron represent the parameters which determine the characteristics and output of a given model cell. These parameters are usually derived from biological data, such as voltage-clamp measurements of ionic conductance characteristics in defined cell types. The range over which these parameters can vary in a given system is referred to as the “parameter space” with a dimensionality dictated by the number of parameters allowed to vary in the system.
One area of interest in neuroscience, and a focus of modeling studies, is the interaction of distinct underlying physiological characteristics in the ultimate...
References
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Schulz, D.J. (2014). Neuronal Parameter Co-regulation. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_170-1
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DOI: https://doi.org/10.1007/978-1-4614-7320-6_170-1
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