Definition
Obstructive sleep apnea (OSA) is characterized by frequent collapse of the upper airways (UAWs) during sleep, and patients with OSA experience many apneas (breathing pauses) during the night.
Description of the Problem
The severity of this condition is graded by the apnea-hypopnea index (AHI) that indicates the number of apneic episodes per hour (normal AHI < 5 and severe AHI > 30). Sleep is therefore interrupted often, and this condition leads to a lowering of oxygen saturation in the blood. These patients often experience many symptoms such as chronic fatigue, impaired memory, congestive heart failure, decreased libido, and hypertension. This is a serious problem that affects 1–4 % of the population (Gislason et al. 1988). Both men and women are affected but in different numbers (Olsen et al. 1995). Several muscles contribute to maintain the patency of the airways with the genioglossus being the strongest contributor by generating tongue extrusion. Other muscles such as...
References
Gislason T, Alquist M, Erikson G, Taube A, Bomem G (1988) Prevalence of sleep apnea syndrome among Swedish men: an epidemiological study. J Clin Epidemiol 61:571–576
Littner M, Hirshkowitz M, Davila D, Anderson WM, Kushida CA, Woodson BT et al (2002) Practice parameters for the use of auto-titrating continuous positive airway pressure devices for titrating pressures and treating adult patients with obstructive sleep apnea syndrome. An American Academy of Sleep Medicine report. Sleep 25(2):143–147
Olsen LG, King MT, Hensley MJ, Saunders NA (1995) A community study of snoring and sleep-disordered breathing prevalence. Am J Respir Crit Care Med 152:711–716
Sahin M, Durand DM, Haxhiu M (1999) Chronic recordings of hypoglossal nerve activity in a dog model of upper airway obstruction. J Appl Physiol 87(6):2297–2206. Also published in Current Awareness in Biomedicine, Neurophysiology, Volume 29, 2000
Schwartz AR, Eisele DW, Smith PL (1998) Pharyngeal airway obstruction in obstructive sleep apnea. Otolaryngol Clin North Am 31(6):911–918
Schwartz AR, Bennett ML, Smith PL, De Backer W, Hedner J, Boudewyns A, Heyning PV, Van deHeyning P, Ejnell H, Hochban W, Knaack L, Podszus T, Penzel T, Hermann J, Goding GS (2001) Therapeutic electrical stimulation of the hypoglossal nerve in obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 127:1216–1223
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this entry
Cite this entry
Durand, D.M. (2014). Peripheral Nerve Interface Applications, Sleep Apnea. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_207-1
Download citation
DOI: https://doi.org/10.1007/978-1-4614-7320-6_207-1
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-7320-6
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences