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Short-Term Synaptic Plasticity in Central Pattern Generators

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Encyclopedia of Computational Neuroscience

Synonyms

Augmentation; Depression; Enhancement; Facilitation; Post-tetanic potentiation

Definition

Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude of the postsynaptic current in response to presynaptic activity. Central pattern generators (CPGs) are neural networks in the central nervous system capable of producing coordinated rhythmic output without rhythmic input from sensory organs or from higher control centers.

Detailed Description

Short-term synaptic plasticity (STP) is a transient (milliseconds to minutes) activity-dependent change in the amplitude (strength) of the postsynaptic current in response to presynaptic activity. It has clear implications for neural signaling and has been studied for several decades. Much of the modeling work has focused on the events in the presynaptic terminal and primarily on the role of Ca2+ in synaptic release of neurotransmitters (Zucker & Regehr 2002; Fioravante and Regehr 2011...

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Acknowledgement

This work was supported in part by NIH grant MH060605.

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Authors and Affiliations

  1. Federated Department of Biological Sciences, Rutgers University, New Jersey Institute of Technology, Newark, NJ, 07102, USA

    Diana Martinez & Farzan Nadim Ph.D.

  2. Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, NJ, USA

    Victor Matveev & Farzan Nadim Ph.D.

Authors
  1. Diana Martinez
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  2. Victor Matveev
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  3. Farzan Nadim Ph.D.
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Correspondence to Diana Martinez .

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Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Martinez, D., Matveev, V., Nadim, F. (2014). Short-Term Synaptic Plasticity in Central Pattern Generators. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_467-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_467-1

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  • Online ISBN: 978-1-4614-7320-6

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