Deep Multiscale Convolutional Feature Learning for Weakly Supervised Localization of Chest Pathologies in X-ray Images

Abstract

Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale feature learning. Our method leverages intermediate feature maps from CNN layers at different stages of a deep network during the training of a classification model using image level annotations of pathologies. During the training phase, a set of layer relevance weights are learned for each pathology class and the CNN is optimized to perform pathology classification by convex combination of feature maps from both shallow and deep layers using the learned weights. During the test phase, to localize the predicted pathology, the multiscale attention map is obtained by convex combination of class activation maps from each stage using the layer relevance weights learned during the training phase. We have validated our method using 112000 X-ray images and compared with the state-of-the-art localization methods. We experimentally demonstrate that the proposed weakly supervised method can improve the localization performance of small pathologies such as nodule and mass while giving comparable performance for bigger pathologies e.g., Cardiomegaly.