Abstract
The effective comparison of biological data sequences is an important and a challenging task in bioinformatics. The sequence alignment process itself is a way of arranging DNA sequences in order to identify similar areas that may have a consequence of functional, structural or evolutionary relations between them. A new effective and unified method for sequence alignment on the basic of trilateration, called CAT method, and using C (cytosine), A (adenine) and T (thymine) benchmarks is presented in this paper. This method suggests solutions to three major problems in sequence alignment: creating a constant favorite sequence, reducing the number of comparisons with the favorite sequence, and unifying/standardizing the favorite sequence by defining benchmark sequences.
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This work is supported by Grant DN07/24.
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Gancheva, V., Stoev, H. (2019). DNA Sequence Alignment Method Based on Trilateration. In: Rojas, I., Valenzuela, O., Rojas, F., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science(), vol 11466. Springer, Cham. https://doi.org/10.1007/978-3-030-17935-9_25
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DOI: https://doi.org/10.1007/978-3-030-17935-9_25
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