Abstract
Total liquid ventilation (TLV) is an innovative experimental method of mechanical ventilation in which lungs are totally filled with a breathable perfluorochemical liquid (PFC). The main objective is to develop a method to estimate the alveolar pressure from a pressure mouth measurement during pause in liquid ventilation. Experimental results show that the measured mouth pressure is disturbed by disturbances (damped oscillations due to fluid-structure tube resonances and cardiogenic oscillation). Numerical analysis of \(P_Y\) allow to obtain a fractional-order model of \(\alpha =0.7\) for the alveolar pressure.
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Vandamme, J., Nadeau, M., Mousseau, J., Praud, JP., Micheau, P. (2019). Model of the Mouth Pressure Signal During Pauses in Total Liquid Ventilation. In: Rojas, I., Valenzuela, O., Rojas, F., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science(), vol 11466. Springer, Cham. https://doi.org/10.1007/978-3-030-17935-9_51
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